منابع مشابه
Role of Pendrin in Acid-base Balance
Pendrin (SLC26A4) is a Na(+)-independent Cl(-)/HCO(3) (-) exchanger which is expressed in the apical membranes of type B and non-A, non-B intercalated cells within the distal convoluted tubule, the connecting tubule, and the cortical collecting duct. In those segments it mediates HCO(3) (-) secretion and chloride (Cl(-)) absorption. In mice, no renal abnormalities are observed under basal condi...
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Pendrin is expressed in the apical regions of type B and non-A, non-B intercalated cells, where it mediates Cl(-) absorption and HCO3(-) secretion through apical Cl(-)/HCO3(-) exchange. Since pendrin is a robust I(-) transporter, we asked whether pendrin is upregulated with dietary I(-) restriction and whether it modulates I(-) balance. Thus I(-) balance was determined in pendrin null and in wi...
متن کاملMedical Acid-base Balance
an increase in the number of poisonings occurring in the province or from an increase in the number of enquiries with no change in the number of poisonings. (ii) there was an increase in 1976 in the number of prescriptions dispensed and therefore an increase in the number of drugs consumed. (iii) the increase in enquiries about poisoning in children, if it reflects an increase in actual poisoni...
متن کاملAcid-base Balance in Sweat
The reaction, the osmotic pressure, and the volume relationships of the body fluids are closely dependent on the properly regulated acid-base equilibrium. We have attempted to work out some of the regulatory mechanisms for the preservat.ion of acidbase equilibrium during the process of heavy sweating in ways analogous to those employed in the many similar studies of blood and urine. The changes...
متن کاملDisorders of Acid-base Balance
Maintenance of acid-base homeostasis is a vital function of the living organism. Deviations of systemic acidity in either direction can impose adverse consequences and when severe can threaten life itself. Acid-base disorders frequently are encountered in the outpatient and especially in the inpatient setting. Effective management of acid-base disturbances, commonly a challenging task, rests wi...
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ژورنال
عنوان ژورنال: Electrolytes & Blood Pressure
سال: 2009
ISSN: 1738-5997
DOI: 10.5049/ebp.2009.7.1.20